Paula Soteropoulos
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Paula Soteropoulos
Chairman of the Board for Ensoma and former CEO of Akcea Therapeutics

Ms. Soteropoulos has more than 30 years of biopharma industry experience in strategic and operational leadership areas including drug development, global commercialization, manufacturing, new company formation and company building. In addition to a strong focus on rare disease, her career spans a broad range of therapeutic areas including cardiovascular and metabolism, neurology, infectious disease, renal, and transplant and oncology. She currently serves as Chairman of the Board of Ensoma, a company she was instrumental in launching from the venture seed stage.  She also serves on the Board of Directors for uniQure, Rallybio, Dianthus and Kyowa Kirin North America.  She is also a strategic advisor to 5AM Ventures and Chiesi Rare Disease.  Previously, she served as founding CEO and member of the Board of Directors of Akcea Therapeutics, leading the company through its IPO and commercial launch of 2 rare disease medicines. Prior to Akcea, she was Senior Vice President and General Manager of Cardiometabolic and Rare Disease Businesses and Strategic Alliances at Moderna. Before Moderna, Ms. Soteropoulos spent more than 20 years at Genzyme Corporation where she held positions of increasing responsibility including Vice President and General Manager, Cardiovascular, Rare Diseases. In this role, Ms. Soteropoulos led all aspects of the cardiovascular business from early portfolio prioritization of science and new business development opportunities through commercialization. Ms. Soteropoulos earned an executive management certificate from the University of Virginia – Darden Graduate School of Business Administration and both Bachelor and Master of Science degrees in Chemical and Biochemical Engineering from Tufts University. Ms. Soteropoulos is in active mentor and coach for Women in Bio Boardroom-ready program and the Termeer Foundation for next-generation entrepreneurs.

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